TY - JOUR
T1 - Statistics for sleep and biological rhythms research
T2 - Longitudinal analysis of biological rhythms data
AU - Klerman, Elizabeth B.
AU - Wang, Wei
AU - Phillips, Andrew J.K.
AU - Bianchi, Matt T.
PY - 2017/2/1
Y1 - 2017/2/1
N2 - This article is part of a Journal of Biological Rhythms series exploring analysis and statistical topics relevant to researchers in biological rhythms and sleep research. The goal is to provide an overview of the most common issues that arise in the analysis and interpretation of data in these fields. In this article, we address issues related to the collection of multiple data points from the same organism or system at different times, since such longitudinal data collection is fundamental to the assessment of biological rhythms. Rhythmic longitudinal data require additional specific statistical considerations, ranging from curve fitting to threshold definitions to accounting for correlation structure. We discuss statistical analyses of longitudinal data including issues of correlational structure and stationarity, markers of biological rhythms, demasking of biological rhythms, and determining phase, waveform, and amplitude of biological rhythms.
AB - This article is part of a Journal of Biological Rhythms series exploring analysis and statistical topics relevant to researchers in biological rhythms and sleep research. The goal is to provide an overview of the most common issues that arise in the analysis and interpretation of data in these fields. In this article, we address issues related to the collection of multiple data points from the same organism or system at different times, since such longitudinal data collection is fundamental to the assessment of biological rhythms. Rhythmic longitudinal data require additional specific statistical considerations, ranging from curve fitting to threshold definitions to accounting for correlation structure. We discuss statistical analyses of longitudinal data including issues of correlational structure and stationarity, markers of biological rhythms, demasking of biological rhythms, and determining phase, waveform, and amplitude of biological rhythms.
KW - Biological rhythms
KW - Circadian rhythms
KW - Longitudinal analyses
KW - Periodicity
KW - Statistics
UR - http://www.scopus.com/inward/record.url?scp=85018719280&partnerID=8YFLogxK
U2 - 10.1177/0748730416670051
DO - 10.1177/0748730416670051
M3 - Review Article
AN - SCOPUS:85018719280
SN - 0748-7304
VL - 32
SP - 18
EP - 25
JO - Journal of Biological Rhythms
JF - Journal of Biological Rhythms
IS - 1
ER -