Statistical shape analysis of hippocampus in temporal lobe epilepsy based on Laplace-Beltrami eigenfunction level sets

Rosita Shishegar, Hamid Soltanian-Zadeh, Farhad Tehranipour

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

Abstract

Shape analysis plays an important role in many medical imaging studies. One of the recent shape analysis methods uses the Laplace Beltrami operator. This article studies the deformation of hippocampus in temporal lobe epilepsy based on Laplace Beltrami operator. The level sets of Laplace Beltrami eigenfunctions are automatically extracted and their circumferences are used as a measure of thickness. Statistical maps of corresponding level sets are computed and visualized using an average atlas. The results suggest significant deformation in both ipsilateral and contralateral hippocampi of epileptic patients. Also it is shown that the pattern of deformation in the seizer side and the other hippocampi are different. Relative to the previous statistical shape analysis studies in epilepsy, the proposed method gives comparable results with the advantage of no need for alignment.
Original languageEnglish
Title of host publicationAISP 2012 - 16th CSI International Symposium on Artificial Intelligence and Signal Processing
Place of PublicationUSA
PublisherIEEE, Institute of Electrical and Electronics Engineers
Pages364-369
Number of pages6
ISBN (Electronic)9781467314787
ISBN (Print)9781467314794
DOIs
Publication statusPublished - 27 Sep 2012
Externally publishedYes
EventCSI International Symposium on Artificial Intelligence and Signal Processing 2012 - Shiraz University, Shiraz, Iran
Duration: 2 May 20123 May 2012
Conference number: 16th
https://www.ieee.org/conferences_events/conferences/conferencedetails/index.html?Conf_ID=20484
http://ieeexplore.ieee.org/xpl/mostRecentIssue.jsp?punumber=6305329 (IEEE Conference Proceedings)

Conference

ConferenceCSI International Symposium on Artificial Intelligence and Signal Processing 2012
Abbreviated titleAISP 2012
CountryIran
CityShiraz
Period2/05/123/05/12
Internet address

Keywords

  • statistical shape analysis
  • laplace beltrami eigenfunctions
  • level set
  • hippocampus
  • epilepsy disease

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