Stabilization of amphiphilic block copolymer nanotubes and vesicles by photopolymerization

R. Kishore, A. Jofre, J. B. Hutchison, M. Allegrini, L. E. Locascio, K. Helmerson

Research output: Chapter in Book/Report/Conference proceedingConference PaperResearchpeer-review

Abstract

We create long polymer nanotubes by directly pulling on the membrane of polymersomes using either optical tweezers or a micropipette. The polymersomes are composed of amphiphilic diblock copolymers and the nanotubes formed have an aqueous core connected to the aqueous interior of the polymersome. Stabilized membranes of nanotubes and vesicles were formed by the directed self-assembly of poly(ethylene oxide)-block-polybutadiene, followed by photopolymerization, initiated by UV light, to a maximum double bond conversion of 15%. The photopolymerized nanotubes are extremely robust. The applicability of photopolymerization for biophysics and bioanalytical science is demonstrated by electrophoresing DNA molecules through a stabilized nanotube with an integrated vesicle reservoir.

Original languageEnglish
Title of host publicationMicro- and Nanotechnology
Subtitle of host publicationMaterials, Processes, Packaging, and Systems III
DOIs
Publication statusPublished - 30 Apr 2007
Externally publishedYes
EventMicro- and Nanotechnology: Materials, Processes, Packaging, and Systems III - Adelaide, Australia
Duration: 11 Dec 200613 Dec 2006

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume6415
ISSN (Print)0277-786X

Conference

ConferenceMicro- and Nanotechnology: Materials, Processes, Packaging, and Systems III
CountryAustralia
CityAdelaide
Period11/12/0613/12/06

Keywords

  • Crosslinking
  • Diblock copolymers
  • DNA electrophoreses
  • Liposomes
  • Membranes
  • Nanotubes
  • Photopolymerization
  • Polymersomes
  • Stability
  • Transport
  • Vesicles

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