Sport related concussion – Potential for biomarkers to improve acute management

Daniel M. Costello; Andrew H. Kaye; Terence J. O'Brien; Sandy R. Shultz

doi:10.1016/j.jocn.2018.07.002

Sport related concussion – Potential for biomarkers to improve acute management

Daniel M. Costello, Andrew H. Kaye, Terence J. O'Brien, Sandy R. Shultz

Department of Neuroscience

Research output: Contribution to journal › Review Article › Other › peer-review

12 Citations (Scopus)

Abstract

Sport-related concussion is a common form of mild traumatic brain injury that is now recognised as a serious health issue. Growing evidence suggests concussion may result in long-term and severe neurological disabilities. Recent research into the diagnosis and management of concussion may provide new approaches to concussion management that limit the potential long-term adverse effects of concussion. This paper summarises the problem of sport-related concussion and reviews key factors (sex, age, genetics) that may modify concussion outcomes. Current sport-related concussion tools are described. Analysis of emerging methods of acute concussion diagnosis using objective fluid and neuroimaging biomarkers is provided. These new concussion biomarkers have the potential to change management of sport-related concussion.

Original language	English
Pages (from-to)	1-6
Number of pages	6
Journal	Journal of Clinical Neuroscience
Volume	56
DOIs	https://doi.org/10.1016/j.jocn.2018.07.002
Publication status	Published - 1 Oct 2018

Keywords

Biomarkers
Blood
Chronic traumatic encephalopathy
Management
Mild traumatic brain injury
MRI

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10.1016/j.jocn.2018.07.002

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abstract = "Sport-related concussion is a common form of mild traumatic brain injury that is now recognised as a serious health issue. Growing evidence suggests concussion may result in long-term and severe neurological disabilities. Recent research into the diagnosis and management of concussion may provide new approaches to concussion management that limit the potential long-term adverse effects of concussion. This paper summarises the problem of sport-related concussion and reviews key factors (sex, age, genetics) that may modify concussion outcomes. Current sport-related concussion tools are described. Analysis of emerging methods of acute concussion diagnosis using objective fluid and neuroimaging biomarkers is provided. These new concussion biomarkers have the potential to change management of sport-related concussion.",

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AU - Kaye, Andrew H.

AU - O'Brien, Terence J.

AU - Shultz, Sandy R.

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KW - MRI

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Sport related concussion – Potential for biomarkers to improve acute management

Abstract

Keywords

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