Spontaneous and reversible self-assembly of a polypeptide fragment of insulin-like growth factor binding protein-2 into fluorescent nanotubular structures

Monalisa Swain; R. Thirupathi; B. Krishnarjuna; Erin M. Eaton; Megan M. Kibbey; Steven A. Rosenzweig; Hanudatta S. Atreya

doi:10.1039/B915775A

Spontaneous and reversible self-assembly of a polypeptide fragment of insulin-like growth factor binding protein-2 into fluorescent nanotubular structures

Monalisa Swain, R. Thirupathi, B. Krishnarjuna, Erin M. Eaton, Megan M. Kibbey, Steven A. Rosenzweig, Hanudatta S. Atreya

Research output: Contribution to journal › Article › Research › peer-review

9 Citations (Scopus)

Abstract

In this communication, we report the spontaneous and reversible in vitro self-assembly of a polypeptide fragment derived from the C-terminal domain of Insulin-like Growth Factor Binding Protein (IGFBP-2) into soluble nanotubular structures several micrometres long via a mechanism involving inter-molecular disulfide bonds and exhibiting enhanced fluorescence.

Original language	English
Article number	1
Pages (from-to)	216-218
Number of pages	3
Journal	Chemical Communications
Volume	46
Issue number	2
DOIs	https://doi.org/10.1039/B915775A https://doi.org/10.1039/b915775a
Publication status	Published - 5 Feb 2010
Externally published	Yes

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Swain, M., Thirupathi, R., Krishnarjuna, B., Eaton, E. M., Kibbey, M. M., Rosenzweig, S. A., & Atreya, H. S. (2010). Spontaneous and reversible self-assembly of a polypeptide fragment of insulin-like growth factor binding protein-2 into fluorescent nanotubular structures. Chemical Communications, 46(2), 216-218. Article 1. https://doi.org/10.1039/B915775A, https://doi.org/10.1039/b915775a

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abstract = "In this communication, we report the spontaneous and reversible in vitro self-assembly of a polypeptide fragment derived from the C-terminal domain of Insulin-like Growth Factor Binding Protein (IGFBP-2) into soluble nanotubular structures several micrometres long via a mechanism involving inter-molecular disulfide bonds and exhibiting enhanced fluorescence.",

author = "Monalisa Swain and R. Thirupathi and B. Krishnarjuna and Eaton, \{Erin M.\} and Kibbey, \{Megan M.\} and Rosenzweig, \{Steven A.\} and Atreya, \{Hanudatta S.\}",

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doi = "10.1039/B915775A",

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journal = "Chemical Communications",

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Swain, M, Thirupathi, R, Krishnarjuna, B, Eaton, EM, Kibbey, MM, Rosenzweig, SA & Atreya, HS 2010, 'Spontaneous and reversible self-assembly of a polypeptide fragment of insulin-like growth factor binding protein-2 into fluorescent nanotubular structures', Chemical Communications, vol. 46, no. 2, 1, pp. 216-218. https://doi.org/10.1039/B915775A, https://doi.org/10.1039/b915775a

TY - JOUR

T1 - Spontaneous and reversible self-assembly of a polypeptide fragment of insulin-like growth factor binding protein-2 into fluorescent nanotubular structures

AU - Swain, Monalisa

AU - Thirupathi, R.

AU - Krishnarjuna, B.

AU - Eaton, Erin M.

AU - Kibbey, Megan M.

AU - Rosenzweig, Steven A.

AU - Atreya, Hanudatta S.

PY - 2010/2/5

Y1 - 2010/2/5

N2 - In this communication, we report the spontaneous and reversible in vitro self-assembly of a polypeptide fragment derived from the C-terminal domain of Insulin-like Growth Factor Binding Protein (IGFBP-2) into soluble nanotubular structures several micrometres long via a mechanism involving inter-molecular disulfide bonds and exhibiting enhanced fluorescence.

AB - In this communication, we report the spontaneous and reversible in vitro self-assembly of a polypeptide fragment derived from the C-terminal domain of Insulin-like Growth Factor Binding Protein (IGFBP-2) into soluble nanotubular structures several micrometres long via a mechanism involving inter-molecular disulfide bonds and exhibiting enhanced fluorescence.

UR - https://www.scopus.com/pages/publications/75649097016

U2 - 10.1039/B915775A

DO - 10.1039/B915775A

M3 - Article

C2 - 20024330

AN - SCOPUS:75649097016

SN - 1359-7345

VL - 46

SP - 216

EP - 218

JO - Chemical Communications

JF - Chemical Communications

IS - 2

M1 - 1

ER -

Spontaneous and reversible self-assembly of a polypeptide fragment of insulin-like growth factor binding protein-2 into fluorescent nanotubular structures

Abstract

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