Sperm dysfunction in the rb(6.16)- and rb(6.15)-bearing mice revisited: Involvement of Hyalp1 and Hyal5

Hong Zhang, Stacy Shertok, Kimberly Miller, Lesley Taylor, Patricia Martin-DeLeon

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21 Citations (Scopus)


Earlier we showed that sperm adhesion molecule1 (Spam 1), the best studied sperm hyaluronidase, is involved in the sperm dysfunction associated with Robertsonian translocations (Rb). The dysfunction results in reduced fertility in mice homozygous for the Rb(6.16) or the Rb(6.15) translocation and transmission ratio distortion (TRD) in heterozygous males.
Original languageEnglish
Pages (from-to)404 - 410
Number of pages7
JournalMolecular Reproduction and Development
Issue number3
Publication statusPublished - 2005
Externally publishedYes

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