Speed-dieting: dopamine agonists promote weight loss

Stephanie E. Simonds; Michael A. Cowley

doi:10.1038/s42255-019-0114-z

Speed-dieting: dopamine agonists promote weight loss

Stephanie E. Simonds, Michael A. Cowley

Research output: Contribution to journal › Article › Other › peer-review

5 Citations (Scopus)

Abstract

Dopamine is an important neurotransmitter with essential roles in movement control and salience, and implications in addiction as well as weight loss, decreased food intake and a reduced motivational drive to eat. Folgueira et al. now demonstrate that dopamine causes weight loss and increases brown adipose tissue temperature via activation of the dopamine receptor D2R in hypothalamic GABA-expressing neurons in mice, and treatment with the dopamine agonist cabergoline causes weight loss in humans.

Original language	English
Pages (from-to)	851-852
Number of pages	2
Journal	Nature Metabolism
Volume	1
Issue number	9
DOIs	https://doi.org/10.1038/s42255-019-0114-z
Publication status	Published - 28 Aug 2019

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10.1038/s42255-019-0114-z

Cite this

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abstract = "Dopamine is an important neurotransmitter with essential roles in movement control and salience, and implications in addiction as well as weight loss, decreased food intake and a reduced motivational drive to eat. Folgueira et al. now demonstrate that dopamine causes weight loss and increases brown adipose tissue temperature via activation of the dopamine receptor D2R in hypothalamic GABA-expressing neurons in mice, and treatment with the dopamine agonist cabergoline causes weight loss in humans.",

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Speed-dieting: dopamine agonists promote weight loss

Abstract

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