Spectroscopic magnetic resonance imaging of a tumefactive demyelinating lesion

M. Law, D. E. Meltzer, S. Cha

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55 Citations (Scopus)


Tumefactive demyelinating lesions can present with features similar, clinically and radiologically, to those of brain tumours. Proton MR spectroscopy has been increasingly used to characterize intracranial pathology. As the underlying pathophysiology of neoplasms is different from that of demyelinating disease, one may expect the metabolic composition of neoplasms to be significantly different from that of demyelinating lesions. We report a 49-year-old woman in whom the neurologic and radiologic findings were highly suggestive of a highgrade brain tumor, and the spectroscopic features were sufficiently similar to that of a tumor to convince the neurosurgeon to operate. This case emphasizes the need for caution when confronted with a patient who presents with a differential diagnosis of demyelinating lesion versus neoplasm.

Original languageEnglish
Pages (from-to)986-989
Number of pages4
Issue number12
Publication statusPublished - 1 Dec 2002
Externally publishedYes


  • Magnetic resonance spectroscopy
  • Multiple sclerosis
  • Tumefactive lesions

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