SOX8 expression during chick embryogenesis

Katrina M. Bell, Patrick S. Western, Andrew H. Sinclair

Research output: Contribution to journalArticleResearchpeer-review

41 Citations (Scopus)

Abstract

We have isolated the SOX8 gene from the chicken embryo. This gene shows a high degree of sequence homology to SOX9 and SOX10. Detailed analysis of SOX8 expression by whole-mount in situ shows a dynamic and restricted expression pattern during chick development. SOX8 is expressed in the somitic derivative, the dermomyotome, the developing heart, pancreas, enteric neurone system, limb and the neural tube. This is the first detailed expression analysis of SOX8 in any species. (C) 2000 Elsevier Science Ireland Ltd.

Original languageEnglish
Pages (from-to)257-260
Number of pages4
JournalMechanisms of Development
Volume94
Issue number1-2
DOIs
Publication statusPublished - 1 Jun 2000

Keywords

  • Chicken embryo
  • Dermomyotome
  • Embryogenesis
  • Enteric neurones
  • Limb development
  • Muscle development
  • Neural tube
  • Pancreas
  • SOX genes
  • SOX8
  • Whole-mount in situ hybridization

Cite this