Sonic hedgehog mediator Gli2 regulates bladder mesenchymal patterning

Wei Cheng, Chung-Kwong Yeung, Yuen-Keng Ng, Jian-Rong Zhang, Chi-Chung Hui, Peter C W Kim

Research output: Contribution to journalArticleResearchpeer-review

29 Citations (Scopus)

Abstract

Congenital bladder anomalies are a major challenge to pediatric urologists. Understanding the mechanism of bladder development is crucial for advancing patient treatment. Current evidence suggests that Shh (R D Systems?) is an epithelial signal regulating bladder development, although the mechanism of the regulation is still unclear. We examined the regulation of bladder mesenchymal development.
Original languageEnglish
Pages (from-to)1543 - 1550
Number of pages8
JournalJournal of Urology
Volume180
Issue number4
DOIs
Publication statusPublished - 2008

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