Sodium Valproate (Epilim) in Refractory Epilepsy

F. J. Vajda; J. J. McNeil; P. Morris; O. Drummer; P. F. Bladin

doi:10.1111/j.1445-5994.1978.tb02402.x

Sodium Valproate (Epilim) in Refractory Epilepsy

F. J. Vajda, J. J. McNeil, P. Morris, O. Drummer, P. F. Bladin

Research output: Contribution to journal › Article › Research › peer-review

2 Citations (Scopus)

Abstract

This study reports the results of treatment of 18 refractory epileptic patients with sodium valproate used as an adjuvant therapy to their previously prescribed medication. Plasma levels of anticonvulsants were monitored throughout this study. Adverse clinical effects and laboratory screening results were reported. A tentative therapeutic plasma level range related to pre‐dosed blood samples of patients receiving sodium valproate is proposed. In 50%, the proportion of days when fits had occurred diminished significantly during valproate therapy especially when accompanied by significant EEG clearing.

Original language	English
Pages (from-to)	46-51
Number of pages	6
Journal	Australian and New Zealand Journal of Medicine
Volume	8
Issue number	1
DOIs	https://doi.org/10.1111/j.1445-5994.1978.tb02402.x
Publication status	Published - 1 Jan 1978
Externally published	Yes

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Sodium Valproate (Epilim) in Refractory Epilepsy

Abstract

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