Small cell variant of anaplastic large cell lymphoma with positive immunoreactivity for CD99

Mohd Sidik Shiran; G. C. Tan; A. R. Sabariah; P. C. Chye; R. Pathmanathan

Small cell variant of anaplastic large cell lymphoma with positive immunoreactivity for CD99

Mohd Sidik Shiran, G. C. Tan, A. R. Sabariah, P. C. Chye, R. Pathmanathan

Research output: Contribution to journal › Article › Other › peer-review

Abstract

A 13 year old boy presented with a huge mass on his right arm of 6 months duration. Histopathological examination revealed sheets of malignant small round blue cells with immunopositivity for LCA, CD43, CD45Ro, CD30, EMA, ALK-1 and CD99, and negativity for CD20, TdT, myogenin, myoD1, NSE, bcl-6, bcl-2 and CD10. Fluorescent In-Situ Hybridization (FISH) testing excluded the diagnosis of Ewing's sarcoma/ PNET. Pathologists need to be aware of the diagnosis of a small cell variant of ALCL, as well as of the fact that CD99 expression commonly occurs in cases of ALK-positive ALCL, in order to distinguish this entity from Ewing's sarcoma/PNET.

Original language	English
Pages (from-to)	150-151
Number of pages	2
Journal	Medical Journal of Malaysia
Volume	63
Issue number	2
Publication status	Published - Jun 2008
Externally published	Yes

Keywords

Anaplastic large cell lymphoma
CD30 positive
CD99 positive
Small cell variant
Soft tissue tumour

Cite this

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title = "Small cell variant of anaplastic large cell lymphoma with positive immunoreactivity for CD99",

abstract = "A 13 year old boy presented with a huge mass on his right arm of 6 months duration. Histopathological examination revealed sheets of malignant small round blue cells with immunopositivity for LCA, CD43, CD45Ro, CD30, EMA, ALK-1 and CD99, and negativity for CD20, TdT, myogenin, myoD1, NSE, bcl-6, bcl-2 and CD10. Fluorescent In-Situ Hybridization (FISH) testing excluded the diagnosis of Ewing's sarcoma/ PNET. Pathologists need to be aware of the diagnosis of a small cell variant of ALCL, as well as of the fact that CD99 expression commonly occurs in cases of ALK-positive ALCL, in order to distinguish this entity from Ewing's sarcoma/PNET.",

keywords = "Anaplastic large cell lymphoma, CD30 positive, CD99 positive, Small cell variant, Soft tissue tumour",

author = "Shiran, {Mohd Sidik} and Tan, {G. C.} and Sabariah, {A. R.} and Chye, {P. C.} and R. Pathmanathan",

year = "2008",

month = jun,

language = "English",

volume = "63",

pages = "150--151",

journal = "Medical Journal of Malaysia",

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TY - JOUR

T1 - Small cell variant of anaplastic large cell lymphoma with positive immunoreactivity for CD99

AU - Shiran, Mohd Sidik

AU - Tan, G. C.

AU - Sabariah, A. R.

AU - Chye, P. C.

AU - Pathmanathan, R.

PY - 2008/6

Y1 - 2008/6

N2 - A 13 year old boy presented with a huge mass on his right arm of 6 months duration. Histopathological examination revealed sheets of malignant small round blue cells with immunopositivity for LCA, CD43, CD45Ro, CD30, EMA, ALK-1 and CD99, and negativity for CD20, TdT, myogenin, myoD1, NSE, bcl-6, bcl-2 and CD10. Fluorescent In-Situ Hybridization (FISH) testing excluded the diagnosis of Ewing's sarcoma/ PNET. Pathologists need to be aware of the diagnosis of a small cell variant of ALCL, as well as of the fact that CD99 expression commonly occurs in cases of ALK-positive ALCL, in order to distinguish this entity from Ewing's sarcoma/PNET.

AB - A 13 year old boy presented with a huge mass on his right arm of 6 months duration. Histopathological examination revealed sheets of malignant small round blue cells with immunopositivity for LCA, CD43, CD45Ro, CD30, EMA, ALK-1 and CD99, and negativity for CD20, TdT, myogenin, myoD1, NSE, bcl-6, bcl-2 and CD10. Fluorescent In-Situ Hybridization (FISH) testing excluded the diagnosis of Ewing's sarcoma/ PNET. Pathologists need to be aware of the diagnosis of a small cell variant of ALCL, as well as of the fact that CD99 expression commonly occurs in cases of ALK-positive ALCL, in order to distinguish this entity from Ewing's sarcoma/PNET.

KW - Anaplastic large cell lymphoma

KW - CD30 positive

KW - CD99 positive

KW - Small cell variant

KW - Soft tissue tumour

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M3 - Article

C2 - 18942305

AN - SCOPUS:55049091229

SN - 0300-5283

VL - 63

SP - 150

EP - 151

JO - Medical Journal of Malaysia

JF - Medical Journal of Malaysia

IS - 2

ER -

Small cell variant of anaplastic large cell lymphoma with positive immunoreactivity for CD99

Abstract

Keywords

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