Skeletal muscle: Functional anatomy and pathophysiology

Dan Exeter, David A. Connell

Research output: Contribution to journalArticleResearchpeer-review

21 Citations (Scopus)


Muscle is generally divided into three subtypesskeletal, cardiac, and smoothbut because this edition focuses on the musculoskeletal system, this article concentrates on skeletal muscle. We review ultrastructure and function and then look at the latest scientific ideas concerning the physiological basis of muscle contraction. It is important to appreciate the different muscle types and how they act with respect to muscle growth and adaptation. Finally, what happens to muscle cells when they are damaged and the reparative response is considered.

Original languageEnglish
Pages (from-to)97-105
Number of pages9
JournalSeminars in Musculoskeletal Radiology
Issue number2
Publication statusPublished - 2010
Externally publishedYes


  • Action potential
  • Contraction
  • Damage
  • Muscle type
  • Myocyte
  • Myofibril
  • Myofilaments
  • Repair
  • Sarcomere

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