Abstract
The absorption and fluorescence spectra of monomeric and aggregated species present in aqueous solutions of porphyrin c have been resolved by steady-state and time-resolved spectroscopy. The dependence of the singlet oxygen formation yield φΔ on excitation wavelength has also been determined. In the Q-band spectral region, the aggregate absorption and emission spectra are shifted to longer wavelengths with respect to the monomer spectrum with φΔ (monomer)= 0.59 and φΔ(aggregate) = 0.33. The relevance of these findings to the optimization of irradiation conditions in tumour phototherapy using porphyrin c are discussed.
| Original language | English |
|---|---|
| Pages (from-to) | 81-89 |
| Number of pages | 9 |
| Journal | Journal of Photochemistry and Photobiology, B: Biology |
| Volume | 3 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1 Jan 1989 |
| Externally published | Yes |
Keywords
- aggregation
- fluorescence
- photosensitizer
- phototherapy.
- Porphyrin c
- singlet oxygen
- time-resolved spectroscopy