Single-site cys-substituting mutation of human lectin galectin-2: modulating solubility in recombinant production, reducing long-term aggregation, and enabling site-specific monoPEGylation

Hui Wang; Lizhong He; Martin Lensch; Hans-Joachim Gabius; Conan Fee; Anton P J Middelberg

doi:10.1021/bm800801b

Single-site cys-substituting mutation of human lectin galectin-2: modulating solubility in recombinant production, reducing long-term aggregation, and enabling site-specific monoPEGylation

Hui Wang, Lizhong He, Martin Lensch, Hans-Joachim Gabius, Conan Fee, Anton P J Middelberg

Research output: Contribution to journal › Article › Research › peer-review

Original language	English
Pages (from-to)	3223 - 3230
Number of pages	8
Journal	Biomacromolecules
Volume	9
Issue number	11
DOIs	https://doi.org/10.1021/bm800801b
Publication status	Published - 2008
Externally published	Yes

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10.1021/bm800801b

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@article{c47db4446f644f7f925e07b434040f4a,

title = "Single-site cys-substituting mutation of human lectin galectin-2: modulating solubility in recombinant production, reducing long-term aggregation, and enabling site-specific monoPEGylation",

author = "Hui Wang and Lizhong He and Martin Lensch and Hans-Joachim Gabius and Conan Fee and Middelberg, {Anton P J}",

year = "2008",

doi = "10.1021/bm800801b",

language = "English",

volume = "9",

pages = "3223 -- 3230",

journal = "Biomacromolecules",

issn = "1525-7797",

publisher = "American Chemical Society",

number = "11",

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Single-site cys-substituting mutation of human lectin galectin-2: modulating solubility in recombinant production, reducing long-term aggregation, and enabling site-specific monoPEGylation. / Wang, Hui; He, Lizhong; Lensch, Martin et al.
In: Biomacromolecules, Vol. 9, No. 11, 2008, p. 3223 - 3230.

Research output: Contribution to journal › Article › Research › peer-review

TY - JOUR

T1 - Single-site cys-substituting mutation of human lectin galectin-2: modulating solubility in recombinant production, reducing long-term aggregation, and enabling site-specific monoPEGylation

AU - Wang, Hui

AU - He, Lizhong

AU - Lensch, Martin

AU - Gabius, Hans-Joachim

AU - Fee, Conan

AU - Middelberg, Anton P J

PY - 2008

Y1 - 2008

UR - http://pubs.acs.org/doi/abs/10.1021/bm800801b

U2 - 10.1021/bm800801b

DO - 10.1021/bm800801b

M3 - Article

SN - 1525-7797

VL - 9

SP - 3223

EP - 3230

JO - Biomacromolecules

JF - Biomacromolecules

IS - 11

ER -

Single-site cys-substituting mutation of human lectin galectin-2: modulating solubility in recombinant production, reducing long-term aggregation, and enabling site-specific monoPEGylation

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