Single-molecule study of dendrimer-hydrocarbon interaction

Karthikeyan Pasupathy; Aaron T. Jones; Pu Chun Ke

Single-molecule study of dendrimer-hydrocarbon interaction

Karthikeyan Pasupathy, Aaron T. Jones, Pu Chun Ke

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › Other › peer-review

Abstract

In this paper we report our study on the interaction of dendrimer and hydrocarbon. The absorbance of generation-3 dendrimer PAMAM (0.25%) was reduced by ∼5% in 60 min with the addition of hydrocarbon Squalane (0.405 mg/mL), possibly due to the phase separation between the PAMAM remained in the solution and the PAMAM bound to the Squalane. Using single-molecule fluorescence microscopy we found that PAMAM molecules in the solution could be immobilized by Squalane molecules coated on a glass substrate, as indicated by the much increased fluorescence intensity of the TRITC-labeled PAMAM in an evanescent wave field. Our study offers the first evidence at the single-molecule level on dendrimer and hydrocarbon interaction and facilitates our understanding of using dendrimers for the prevention of gas hydrates for the petroleum industry.

Original language	English
Title of host publication	2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings
Pages	283-286
Number of pages	4
Volume	1
Publication status	Published - 24 Aug 2007
Externally published	Yes
Event	Nanotechnology Conference and Trade Show (Nanotech) 2007 - Santa Clara, United States of America Duration: 20 May 2007 → 24 May 2007

Conference

Conference	Nanotechnology Conference and Trade Show (Nanotech) 2007
Abbreviated title	NSTI Nanotech 2007
Country/Territory	United States of America
City	Santa Clara
Period	20/05/07 → 24/05/07

Keywords

Fluorescence
PAMAM
Squalane

Cite this

@inproceedings{f969eed6318b47bd96e0c73b73a4ba03,

title = "Single-molecule study of dendrimer-hydrocarbon interaction",

abstract = "In this paper we report our study on the interaction of dendrimer and hydrocarbon. The absorbance of generation-3 dendrimer PAMAM (0.25%) was reduced by ∼5% in 60 min with the addition of hydrocarbon Squalane (0.405 mg/mL), possibly due to the phase separation between the PAMAM remained in the solution and the PAMAM bound to the Squalane. Using single-molecule fluorescence microscopy we found that PAMAM molecules in the solution could be immobilized by Squalane molecules coated on a glass substrate, as indicated by the much increased fluorescence intensity of the TRITC-labeled PAMAM in an evanescent wave field. Our study offers the first evidence at the single-molecule level on dendrimer and hydrocarbon interaction and facilitates our understanding of using dendrimers for the prevention of gas hydrates for the petroleum industry.",

keywords = "Fluorescence, PAMAM, Squalane",

author = "Karthikeyan Pasupathy and Jones, {Aaron T.} and Ke, {Pu Chun}",

year = "2007",

month = aug,

day = "24",

language = "English",

isbn = "1420063421",

volume = "1",

pages = "283--286",

booktitle = "2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings",

note = "Nanotechnology Conference and Trade Show (Nanotech) 2007 , NSTI Nanotech 2007 ; Conference date: 20-05-2007 Through 24-05-2007",

}

TY - GEN

T1 - Single-molecule study of dendrimer-hydrocarbon interaction

AU - Pasupathy, Karthikeyan

AU - Jones, Aaron T.

AU - Ke, Pu Chun

PY - 2007/8/24

Y1 - 2007/8/24

N2 - In this paper we report our study on the interaction of dendrimer and hydrocarbon. The absorbance of generation-3 dendrimer PAMAM (0.25%) was reduced by ∼5% in 60 min with the addition of hydrocarbon Squalane (0.405 mg/mL), possibly due to the phase separation between the PAMAM remained in the solution and the PAMAM bound to the Squalane. Using single-molecule fluorescence microscopy we found that PAMAM molecules in the solution could be immobilized by Squalane molecules coated on a glass substrate, as indicated by the much increased fluorescence intensity of the TRITC-labeled PAMAM in an evanescent wave field. Our study offers the first evidence at the single-molecule level on dendrimer and hydrocarbon interaction and facilitates our understanding of using dendrimers for the prevention of gas hydrates for the petroleum industry.

AB - In this paper we report our study on the interaction of dendrimer and hydrocarbon. The absorbance of generation-3 dendrimer PAMAM (0.25%) was reduced by ∼5% in 60 min with the addition of hydrocarbon Squalane (0.405 mg/mL), possibly due to the phase separation between the PAMAM remained in the solution and the PAMAM bound to the Squalane. Using single-molecule fluorescence microscopy we found that PAMAM molecules in the solution could be immobilized by Squalane molecules coated on a glass substrate, as indicated by the much increased fluorescence intensity of the TRITC-labeled PAMAM in an evanescent wave field. Our study offers the first evidence at the single-molecule level on dendrimer and hydrocarbon interaction and facilitates our understanding of using dendrimers for the prevention of gas hydrates for the petroleum industry.

KW - Fluorescence

KW - PAMAM

KW - Squalane

UR - http://www.scopus.com/inward/record.url?scp=34548010287&partnerID=8YFLogxK

M3 - Conference Paper

AN - SCOPUS:34548010287

SN - 1420063421

SN - 9781420063424

SN - 1420061828

SN - 9781420061826

VL - 1

SP - 283

EP - 286

BT - 2007 NSTI Nanotechnology Conference and Trade Show - NSTI Nanotech 2007, Technical Proceedings

T2 - Nanotechnology Conference and Trade Show (Nanotech) 2007

Y2 - 20 May 2007 through 24 May 2007

ER -

Single-molecule study of dendrimer-hydrocarbon interaction

Abstract

Conference

Keywords

Other files and links

Single-Molecule Dendrimer-Hydrocarbon Interaction

Cite this