Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation

Naatasha Isahak; Guillaume Gody; Lara R Malins; Nicholas J Mitchell; Richard James Payne; Sebastien Perrier

doi:10.1039/c6cc06010b

Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation

Naatasha Isahak, Guillaume Gody, Lara R Malins, Nicholas J Mitchell, Richard James Payne, Sebastien Perrier

Drug Delivery Disposition & Dynamics

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15 Citations (Scopus)

Abstract

A novel method for the introduction of a single protected amine-functional monomer at the chain end of RAFT polymers has been developed. This monomer addition, in concert with native chemical ligation, facilitated the development of a simple and versatile method for the end-functionalization of polymers with peptides.

Original language	English
Pages (from-to)	12952-12955
Number of pages	4
Journal	Chemical Communications
Volume	52
Issue number	88
DOIs	https://doi.org/10.1039/c6cc06010b
Publication status	Published - 2016

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title = "Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation",

abstract = "A novel method for the introduction of a single protected amine-functional monomer at the chain end of RAFT polymers has been developed. This monomer addition, in concert with native chemical ligation, facilitated the development of a simple and versatile method for the end-functionalization of polymers with peptides.",

author = "Naatasha Isahak and Guillaume Gody and Malins, \{Lara R\} and Mitchell, \{Nicholas J\} and Payne, \{Richard James\} and Sebastien Perrier",

year = "2016",

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T1 - Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation

AU - Isahak, Naatasha

AU - Gody, Guillaume

AU - Malins, Lara R

AU - Mitchell, Nicholas J

AU - Payne, Richard James

AU - Perrier, Sebastien

PY - 2016

Y1 - 2016

N2 - A novel method for the introduction of a single protected amine-functional monomer at the chain end of RAFT polymers has been developed. This monomer addition, in concert with native chemical ligation, facilitated the development of a simple and versatile method for the end-functionalization of polymers with peptides.

AB - A novel method for the introduction of a single protected amine-functional monomer at the chain end of RAFT polymers has been developed. This monomer addition, in concert with native chemical ligation, facilitated the development of a simple and versatile method for the end-functionalization of polymers with peptides.

UR - https://www.scopus.com/pages/publications/84994056574

U2 - 10.1039/c6cc06010b

DO - 10.1039/c6cc06010b

M3 - Article

AN - SCOPUS:84994056574

SN - 1359-7345

VL - 52

SP - 12952

EP - 12955

JO - Chemical Communications

JF - Chemical Communications

IS - 88

ER -

Single addition of an allylamine monomer enables access to end-functionalized RAFT polymers for native chemical ligation

Abstract

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