Simplified platensimycin analogues as antibacterial agents

Dragan Krsta, Ka Uen Caron Ku, Ian Travers Crosby, Benvenuto Capuano, David Thomas Manallack

Research output: Contribution to journalArticleResearchpeer-review

1 Citation (Scopus)

Abstract

A series of substituted 2-hydroxybenzoic acid derivatives were synthesized as simplified analogues of platensimycin. The final compounds were evaluated against the Gram-positive bacteria, methicillin-resistant Staphylococcus aureus. Analogues that possessed polycyclic groups directly attached to the substituted benzoic acid were able to demonstrate modest antimicrobial activity.
Original languageEnglish
Pages (from-to)244 - 249
Number of pages6
JournalMedChemComm
Volume3
Issue number2
DOIs
Publication statusPublished - 2012

Cite this

Krsta, Dragan ; Ku, Ka Uen Caron ; Crosby, Ian Travers ; Capuano, Benvenuto ; Manallack, David Thomas. / Simplified platensimycin analogues as antibacterial agents. In: MedChemComm. 2012 ; Vol. 3, No. 2. pp. 244 - 249.
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Simplified platensimycin analogues as antibacterial agents. / Krsta, Dragan; Ku, Ka Uen Caron; Crosby, Ian Travers; Capuano, Benvenuto; Manallack, David Thomas.

In: MedChemComm, Vol. 3, No. 2, 2012, p. 244 - 249.

Research output: Contribution to journalArticleResearchpeer-review

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