Sildenafil therapy in bronchopulmonary dysplasia-associated pulmonary hypertension: a retrospective study of efficacy and safety

Kenneth Hark Hong Tan, Mohan Krishnamurthy, Josie L O'Heney, Eldho Paul, Arvind Sehgal

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Bronchopulmonary dysplasia (BPD) is associated with a high incidence of pulmonary artery hypertension (PAH) and is frequently treated with sildenafil. The objective was to investigate the echocardiographic and clinical efficacy and safety of sildenafil in this setting. The hypothesis was that treatment would result in significant echocardiographic and clinical improvements. This was a retrospective study of the cohort of infants who were born between 2004 and 2012 and administered sildenafil as in-patients for BPD-associated PAH
Original languageEnglish
Pages (from-to)1109 - 1115
Number of pages7
JournalEuropean Journal of Pediatrics
Issue number8
Publication statusPublished - 2015

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