Shutting the gate: targeting endocytosis in acute leukemia

Cedric S. Tremblay; Stephen B. Ting; Adam McCluskey; Phillip J. Robinson; David J. Curtis

doi:10.1016/j.exphem.2021.09.003

Shutting the gate: targeting endocytosis in acute leukemia

Cedric S. Tremblay, Stephen B. Ting, Adam McCluskey, Phillip J. Robinson, David J. Curtis

Australian Centre for Blood Diseases

Research output: Contribution to journal › Review Article › Other › peer-review

1 Citation (Scopus)

Abstract

Endocytosis entails selective packaging of cell surface cargos in cytoplasmic vesicles, thereby controlling key intrinsic cellular processes as well as the response of normal and malignant cells to their microenvironment. The purpose of this review is to outline the latest advances in the development of endocytosis-targeting therapeutic strategies in hematological malignancies.

Original language	English
Pages (from-to)	17-31
Number of pages	15
Journal	Experimental Hematology
Volume	104
DOIs	https://doi.org/10.1016/j.exphem.2021.09.003
Publication status	Published - Dec 2021

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@article{db17f7aa108647f5b2bcda3974340d05,

title = "Shutting the gate: targeting endocytosis in acute leukemia",

abstract = "Endocytosis entails selective packaging of cell surface cargos in cytoplasmic vesicles, thereby controlling key intrinsic cellular processes as well as the response of normal and malignant cells to their microenvironment. The purpose of this review is to outline the latest advances in the development of endocytosis-targeting therapeutic strategies in hematological malignancies.",

author = "Tremblay, {Cedric S.} and Ting, {Stephen B.} and Adam McCluskey and Robinson, {Phillip J.} and Curtis, {David J.}",

note = "Publisher Copyright: {\textcopyright} 2021 ISEH — Society for Hematology and Stem Cells",

year = "2021",

month = dec,

doi = "10.1016/j.exphem.2021.09.003",

language = "English",

volume = "104",

pages = "17--31",

journal = "Experimental Hematology",

issn = "0301-472X",

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TY - JOUR

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T2 - targeting endocytosis in acute leukemia

AU - Tremblay, Cedric S.

AU - Ting, Stephen B.

AU - McCluskey, Adam

AU - Robinson, Phillip J.

AU - Curtis, David J.

PY - 2021/12

Y1 - 2021/12

N2 - Endocytosis entails selective packaging of cell surface cargos in cytoplasmic vesicles, thereby controlling key intrinsic cellular processes as well as the response of normal and malignant cells to their microenvironment. The purpose of this review is to outline the latest advances in the development of endocytosis-targeting therapeutic strategies in hematological malignancies.

AB - Endocytosis entails selective packaging of cell surface cargos in cytoplasmic vesicles, thereby controlling key intrinsic cellular processes as well as the response of normal and malignant cells to their microenvironment. The purpose of this review is to outline the latest advances in the development of endocytosis-targeting therapeutic strategies in hematological malignancies.

UR - http://www.scopus.com/inward/record.url?scp=85120436364&partnerID=8YFLogxK

U2 - 10.1016/j.exphem.2021.09.003

DO - 10.1016/j.exphem.2021.09.003

M3 - Review Article

C2 - 34563604

AN - SCOPUS:85120436364

SN - 0301-472X

VL - 104

SP - 17

EP - 31

JO - Experimental Hematology

JF - Experimental Hematology

ER -

Shutting the gate: targeting endocytosis in acute leukemia

Abstract

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