TY - JOUR
T1 - Short-term morbidity associated with sentinel lymph node biopsy in cutaneous malignant melanoma
AU - Ling, Adrian James
AU - Dawkins, Rosie
AU - Bailey, Michael John
AU - Leung, Michael
AU - Cleland, Heather J
AU - Serpell, Jonathan
AU - Kelly, John
PY - 2010
Y1 - 2010
N2 - Guidelines for the surgical treatment of cutaneous primary malignant melanoma are well established; however, the approach to the treatment of the regional lymph nodes remains more controversial. In many centres, sentinel lymph node biopsy has been adopted as routine in the treatment of malignant melanoma for prognostic purposes, as it is not of proven therapeutic benefit. The Multicentre Selective Lymphadenectomy Trial II aims to determine the comparative benefits of subsequent completion lymphadenectomy versus observation in those found to have a positive sentinel node biopsy. Until results are available, the risks of the procedure must be weighed against the value of prognostic information gained from performing a sentinel node biopsy. In this retrospective
analysis of sentinel lymph node biopsies at
our institution, we show that in general, short-term
morbidity associated with this procedure is low, but
that morbidity is higher in a subgroup of people with
higher weight or body mass index, and in those whose
biopsy is located in the groin.
AB - Guidelines for the surgical treatment of cutaneous primary malignant melanoma are well established; however, the approach to the treatment of the regional lymph nodes remains more controversial. In many centres, sentinel lymph node biopsy has been adopted as routine in the treatment of malignant melanoma for prognostic purposes, as it is not of proven therapeutic benefit. The Multicentre Selective Lymphadenectomy Trial II aims to determine the comparative benefits of subsequent completion lymphadenectomy versus observation in those found to have a positive sentinel node biopsy. Until results are available, the risks of the procedure must be weighed against the value of prognostic information gained from performing a sentinel node biopsy. In this retrospective
analysis of sentinel lymph node biopsies at
our institution, we show that in general, short-term
morbidity associated with this procedure is low, but
that morbidity is higher in a subgroup of people with
higher weight or body mass index, and in those whose
biopsy is located in the groin.
UR - http://onlinelibrary.wiley.com/doi/10.1111/j.1440-0960.2009.00575.x/pdf
U2 - 10.1111/j.1440-0960.2009.00575.x
DO - 10.1111/j.1440-0960.2009.00575.x
M3 - Article
SN - 0004-8380
VL - 51
SP - 13
EP - 17
JO - Australasian Journal of Dermatology
JF - Australasian Journal of Dermatology
IS - 1
ER -