Short-term meal replacements followed by dietary macronutrient restriction enhance weight loss in polycystic ovary syndrome

Lisa Jane Moran, Manny Noakes, Peter M Clifton, Gary G Wittert, Gemma Williams, Robert J Norman

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92 Citations (Scopus)


BACKGROUND: Polycystic ovary syndrome (PCOS), a common condition in women, improves with weight loss. Meal replacements in short-term weight loss and strategies for weight maintenance have not been investigated in PCOS. OBJECTIVE: We compared in overweight women with PCOS the effects of meal replacements in short-term weight-loss and longer-term carbohydrate- or fat-restriction strategies on weight maintenance and improvements in reproductive and metabolic variables. DESIGN: Overweight women with PCOS (n = 43; x +/- SD age: 32.1 +/- 5.2 y; weight: 96.1 +/- 18.4 kg) followed an 8-wk weight-loss regimen (2 meal replacements/d, 4904.4 +/- 127 kJ; phase 1) and then a 6-mo weight-maintenance carbohydrate- (
Original languageEnglish
Pages (from-to)77 - 87
Number of pages11
JournalAmerican Journal of Clinical Nutrition
Issue number1
Publication statusPublished - 2006

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