Shock-like haemodynamic responses induced in the primary visual cortex by moving visual stimuli

T. C. Lacy, K. M. Aquino, Peter Alexander Robinson, M. M. Schira

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5 Citations (Scopus)

Abstract

It is shown that recently discovered haemodynamic waves can form shocklike fronts when driven by stimuli that excite the cortex in a patch that moves faster than the haemodynamic wave velocity. If stimuli are chosen in order to induce shock-like behaviour, the resulting blood oxygen level-dependent (BOLD) response is enhanced, thereby improving the signal to noise ratio of measurements made with functional magnetic resonance imaging. A spatiotemporal haemodynamic model is extended to calculate the BOLD response and determine the main properties of waves induced by moving stimuli. From this, the optimal conditions for stimulating shock-like responses are determined, and ways of inducing these responses in experiments are demonstrated in a pilot study.

Original languageEnglish
Article number20160576
Number of pages15
JournalJournal of the Royal Society Interface
Volume13
Issue number125
DOIs
Publication statusPublished - 31 Dec 2016
Externally publishedYes

Keywords

  • Blood oxygen level dependent (BOLD)
  • Functional magnetic resonance imaging
  • Haemodynamics
  • Shocks
  • Spatio-temporal

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