Sheep as a model species for the study and treatment of human asthma and other respiratory diseases

Els N. Meeusen, Kenneth J. Snibson, Stuart J. Hirst, Robert J. Bischof

Research output: Contribution to journalReview ArticleResearchpeer-review

40 Citations (Scopus)

Abstract

Classic studies in sheep have contributed greatly to our understanding of lung physiology in health and disease. Similarities in size and structure between sheep and human lungs allow testing of new treatments using the same equipment and procedures used in human medicine, thereby facilitating translation of findings into the clinic. Sheep models of respiratory diseases, in particular sheep models of asthma, continue to be refined and provide unique opportunities for both basic and applied studies of respiratory diseases and their treatments.

Original languageEnglish
Pages (from-to)101-106
Number of pages6
JournalDrug Discovery Today: Disease Models
Volume6
Issue number4
DOIs
Publication statusPublished - Dec 2009

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