Sequence-directed dynamic covalent assembly of base-4-encoded oligomers

S. C. Leguizamon, M. F. Dunn, T. F. Scott

Research output: Contribution to journalArticleResearchpeer-review

2 Citations (Scopus)

Abstract

As an information-bearing biomacromolecule, DNA is encoded in base-4, where each residue site can be occupied by any one of four nucleobases. Mimicking the information dense, sequence-selective hybridization of DNA, we demonstrate two orthogonal dynamic covalent interactions to effect the selective assembly of molecular ladders and grids from base-4-encoded oligo(peptoid)s.

Original languageEnglish
Pages (from-to)7817-7820
Number of pages4
JournalChemical Communications
Volume56
DOIs
Publication statusPublished - 18 Jul 2020

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