Abstract
Peptide self-assembly has been exploited to generate a multitude of biomaterials that exhibit biocompatibility due to their similarity to naturally occurring proteins. Previously, we have shown that β-tripeptides self-assemble despite containing sterically bulky, functional sidechains. Herein, we describe the synthesis of a novel β-amino acid to allow for the synthesis of a trifunctional β-tripeptide that remarkably maintains self-assembly and acts as a bioactive neuronal scaffold. These scaffolds show promise for studies involving neuronal cell growth and development.
Original language | English |
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Pages (from-to) | 4475-4479 |
Number of pages | 5 |
Journal | Journal of Materials Chemistry B |
Volume | 9 |
Issue number | 22 |
DOIs | |
Publication status | Published - 14 Jun 2021 |