A range of lipophilic cyclodextrin derivatives, including 2,6-didodecyl-α- and -β-cyclodextrins, and 2,3,6-tri-O-ethyl-β- cyclodextrin, has been examined as ionophores in electrode response studies of the detection of guanidine, alkylated guanidines, creatinine and several tetraalkylammonium ions including choline, acetylcholine and the long-chain cationic surfactants CnH2n + 1NMe3+ (n = 8 → 16). Interference from Group Ia and IIa cations is minimal for alkylammonium ions (-log kpot > 4 typically) and in certain cases binding of the ion has been further defined by electrospray mass spectrometric and NMR methods.
|Number of pages||9|
|Journal||Journal of the Chemical Society, Perkin Transactions 2|
|Publication status||Published - 1 Dec 1995|