Screening for glycaemic abnormalities in PCOS: an ongoing controversy

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In the current issue of Human Reproduction, Veltman-Verhulst et al. (2013) have explored a controversial area of clinical importance screening of youngwomenwith polycystic ovary syndrome(PCOS) for diabetes abnormalities. In a cross-sectional study of 229 women with PCOS attending an infertility service, the authors evaluate a two-step screening process for the detection of diabetes. They conclude that diabetes patients could potentially be found by initial fasting glucose assessment followed by an oral glucose tolerance test (OGTT) only in patients with fasting glucose between 6.1 and 7.0 mmol/l. This commentary on the study by Veltman-Verhulst et al. highlights the need to consider levels of dysglycaemia lower than that of frank diabetes and emphasizes the need for further research into the metabolic impact ofPCOSand into optimal screening approaches for glycaemic abnormalities in this highrisk group of reproductive age women.
Original languageEnglish
Pages (from-to)2024 - 2025
Number of pages2
JournalHuman Reproduction
Issue number8
Publication statusPublished - 2013

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