Screening behavior in women at increased familial risk for breast cancer

C. Yoland Antill, John Reynolds, Mary Anne Young,  ˙ Judy A. Kirk, Katherine M. Tucker, Tarli L. Bogtstra,  ˙ Shirley S. Wong,  ˙ Tracy E. Dudding, Juliana L. Di Iulio, Kelly-Anne Phillips

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32 Citations (Scopus)


This multicenter study examined the adherence of high-risk women to screening recommendations for breast and ovarian cancer following consultation at a familial cancer clinic (FCC). Self-report questionnaires assessing recall of screening advice, tests undertaken, risk perception, anxiety (Impact of Events Scale) and demographics were mailed to 396 consecutive eligible women who had attended one of six FCCs a median of 3.6 years prior. Family history, genetic test results and screening recommendations were abstracted from medical records. 182/266 (68.4%) women responded with 130 lost to follow-up. The proportions of women undertaking at least the recommended frequency of screening tests were: breast␣self examination (BSE) 50.4%, clinical breast examination (CBE) 66.0%, mammography 82.2%, transvaginal ultrasound (TVUS) 70.0%, CA125 84.0%. Factors associated with adherence to screening were: higher anxiety for BSE and CBE, being BRCA1/2 positive for CBE, older age, method of arrangement and having at least one affected first degree relative for mammography. Factors significantly associated with over-adherence were higher scores for anxiety for BSE and CBE and younger age (
Original languageEnglish
Pages (from-to)359-368
Number of pages10
JournalFamilial Cancer
Issue number4
Publication statusPublished - 2006

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