Scanning electrochemical microscopy (SECM) studies of oxygen transfer across phospholipid monolayers under surface pressure control: comparison of monolayers at air/water and oil/water interfaces

Susan Cannan, Jie Zhang, Frank Grunfeld, Patrick R. Unwin

Research output: Contribution to journalArticleResearchpeer-review

20 Citations (Scopus)


Scanning electrochemical microscopy has been used in combination with a specially designed Langmuir trough to compare the kinetics of oxygen transfer across an L-α-phosphatidylethanolamine, distearoyl monolayer spread at three different interfaces: air/water, air/water in contact with an oil lens, and oil/ water. The monolayer is shown to reduce the kinetics of interfacial transport, and rate constants for the transport of oxygen across each interface, at different surface pressures, have been evaluated. The results obtained for each interface are compared, and the implications for studies of passive diffusion across cell membranes are discussed.

Original languageEnglish
Pages (from-to)701-707
Number of pages7
Issue number3
Publication statusPublished - 3 Feb 2004
Externally publishedYes

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