Sarcopenic obesity and dynapenic obesity: 5-year associations with falls risk in middle-aged and older adults

David Scott, Kerrie Margaret Sanders, Dawn Aitken, Alan Hayes, Peter Robert Ebeling, Graeme Jones

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88 Citations (Scopus)


OBJECTIVES: To determine whether obesity concurrent with sarcopenia (low muscle mass) or dynapenia (low muscle strength) is associated with increased falls risk in middle-aged and older adults. METHODS: 5-year prospective cohort study including 674 community-dwelling volunteers (mean???SD age 61.4???7.0 years; 48 female). Sarcopenia and dynapenia were defined as lowest sex-specific tertiles for dual-energy X-ray (DXA)-assessed appendicular lean mass (adjusted for height and fat mass) or lower-limb strength, respectively. Obesity was defined as the highest tertiles of DXA-assessed total or trunk fat mass. Change in falls risk was calculated using the Physiological Profile Assessment (z-scores: 0-1?=?mild increased risk; 1-2?=?moderate increased risk; >2?=?marked increased risk). RESULTS: Multivariable linear regression analyses revealed mild but significantly increased falls risk scores for dynapenic obesity (change in mean z-score compared to non-dynapenic, non-obese group: 0.33, 95 CI 0.06-0.59 [men] and 0.46, 95 CI 0.21-0.72 [women]) and dynapenia (0.25, 95 CI 0.05-0.46 [women only]). CONCLUSIONS: Dynapenic obesity, but not sarcopenic obesity, is predictive of increased falls risk score in middle-aged and older adults. In clinical settings, muscle function assessments may be useful for predicting falls risk in obese patients.
Original languageEnglish
Pages (from-to)1568 - 1574
Number of pages7
Issue number6
Publication statusPublished - 2014

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