TY - JOUR
T1 - Safety of the Polish BCG-10 Vaccine during a Period of BCG Vaccine Shortage
T2 - An Australian Experience
AU - Wong, Nicole X.
AU - Buttery, Jim
AU - McMinn, Alissa
AU - Azhar, Zainul
AU - Crawford, Nigel W.
PY - 2020/6
Y1 - 2020/6
N2 - Bacille Calmete-Guerin vaccine is widely administered to reduce the risk of severe tuberculosis disease in children. Recent global vaccine supply issues have led to the use of alternative products, which may vary in side effect profile. We report on the safety of the Polish (Moreau strain) "Bacille Calmete-Guerin-10" vaccine in an Australian cohort. Using active surveillance, we identified an adverse event rate of 54.6 per 10,000 doses (95% confidence interval: 38.5-75.2), which was comparable to that reported with the Danish Sanofi-Pasteur and Connaught strains.
AB - Bacille Calmete-Guerin vaccine is widely administered to reduce the risk of severe tuberculosis disease in children. Recent global vaccine supply issues have led to the use of alternative products, which may vary in side effect profile. We report on the safety of the Polish (Moreau strain) "Bacille Calmete-Guerin-10" vaccine in an Australian cohort. Using active surveillance, we identified an adverse event rate of 54.6 per 10,000 doses (95% confidence interval: 38.5-75.2), which was comparable to that reported with the Danish Sanofi-Pasteur and Connaught strains.
KW - adverse events following immunization
KW - Bacille Calmete-Guerin
KW - vaccine safety
UR - http://www.scopus.com/inward/record.url?scp=85084694950&partnerID=8YFLogxK
U2 - 10.1097/INF.0000000000002630
DO - 10.1097/INF.0000000000002630
M3 - Article
C2 - 32150004
AN - SCOPUS:85084694950
SN - 0891-3668
VL - 39
SP - E66-E68
JO - The Pediatric Infectious Disease Journal
JF - The Pediatric Infectious Disease Journal
IS - 6
ER -
