Safety and Efficacy of Selective Anti-Hypertensive Drugs in Patients with Cardiovascular Diseases: An Observational Study

R. E. Ugandar, Umadevi Iluru, Mariamma Bethe, C. Bhargava Reddy , A. Sai Keshava Reddy, Kiran C. Nilugal, Nagashekhara Molugulu, Venkata Ramana Baru, K. Anusha

Research output: Chapter in Book/Report/Conference proceedingChapter (Book)Other


The study was conducted to determine the safest and most effective drug among various categories of anti-hypertensive drugs to treat hypertension in patients with various cardiovascular diseases. Hypertension is a condition with persistent elevation of Blood Pressure in arteries. It is the second leading cause of death. The complex interaction of genes and environmental factors results in hypertension. Severe headache, drowsiness, vision problems, nosebleed, fatigue, and confusion are among the symptoms. It can cause a variety of cardiovascular problems, including myocardial infarction, coronary artery disease, and heart failure. The treatment of Hypertension can be done by Anti-Hypertensive Drugs which include Angiotensin-II Receptor Blockers, Beta Blockers, Angiotensin Converting Enzyme Inhibitors, etc. The study involved a sample size of 220 out of which 100 were Myocardial Infarction patients,100 were coronary artery disease patients and 20 were Heart Failure patients. Angiotensin-II Receptor Blockers, Beta Blockers, and Angiotensin Converting Enzyme Inhibitors were the antihypertensive drugs chosen for the study. Angiotensin-II Receptor Blockers were prescribed to 31 Myocardial Infarction patients, 31 coronary artery disease patients, and 8 Heart Failure patients. Beta Blockers were prescribed to 58 patients with myocardial infarction, 58 patients with coronary artery disease, and 7 patients with heart failure. Angiotensin Converting. Enzyme Inhibitors were prescribed to 10 Myocardial Infarction patients,10 Coronary Artery Disease patients, and 5 Heart Failure patients. The study revealed an outcome in which Beta Blockers were observed to be the drugs with maximum efficacy and maximum safety.

Keywords: Hypertension myocardial infarction coronary artery disease heart failure beta blockers
Original languageEnglish
Title of host publicationCurrent Overview on Pharmaceutical Science
EditorsJohn Yahya I. Elshimali
Place of PublicationUnited States
PublisherB P International
Number of pages15
ISBN (Electronic)9788119039241
ISBN (Print)9788119039289
Publication statusPublished - 20 Jan 2023

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