Safety and effectiveness of endovascular embolization or stent-graft reconstruction for treatment of acute carotid blowout syndrome in patients with head and neck cancer

Case series and systematic review of observational studies

Daniel J. Y. Wong, Christopher Donaldson, Leon T. Lai, Andrew Coleman, Charles Giddings, Lee-Anne Slater, Ronil V. Chandra

Research output: Contribution to journalReview ArticleResearchpeer-review

4 Citations (Scopus)

Abstract

Background: Indications for treatment and outcomes after endovascular management of carotid blowout syndrome for patients with head and neck cancer are not well defined. We investigated the safety and effectiveness of endovascular embolization and stent-graft reconstruction. Methods: A literature review was performed for studies published between 2001 and 2015 with relevance to treatment outcomes. Our institutional database was examined to identify patients treated with endovascular techniques. Results: A total of 266 patients were included. Rates of procedural stroke were higher after embolization of internal carotid artery (ICA)/common carotid artery (CCA) compared to stent graft (embolization 10.3%; stent graft 2.5%; P<.02). Stent graft of ICA/CCA was associated with higher rates of recurrent bleeding (embolization 9.1%; stent graft 31.9%; P<.01). Conclusion: Both embolization and stent grafts are safe therapeutic options for acute carotid blowout syndrome. Embolization for ICA/CCA carotid blowout syndrome was associated with higher risks of procedural stroke and lower recurrent bleeding compared to stent grafts.

Original languageEnglish
Pages (from-to)846-854
Number of pages9
JournalHead and Neck
Volume40
Issue number4
DOIs
Publication statusPublished - Apr 2018

Keywords

  • Carotid blowout syndrome
  • Embolization
  • Endovascular
  • Stent graft
  • Systematic review

Cite this

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title = "Safety and effectiveness of endovascular embolization or stent-graft reconstruction for treatment of acute carotid blowout syndrome in patients with head and neck cancer: Case series and systematic review of observational studies",
abstract = "Background: Indications for treatment and outcomes after endovascular management of carotid blowout syndrome for patients with head and neck cancer are not well defined. We investigated the safety and effectiveness of endovascular embolization and stent-graft reconstruction. Methods: A literature review was performed for studies published between 2001 and 2015 with relevance to treatment outcomes. Our institutional database was examined to identify patients treated with endovascular techniques. Results: A total of 266 patients were included. Rates of procedural stroke were higher after embolization of internal carotid artery (ICA)/common carotid artery (CCA) compared to stent graft (embolization 10.3{\%}; stent graft 2.5{\%}; P<.02). Stent graft of ICA/CCA was associated with higher rates of recurrent bleeding (embolization 9.1{\%}; stent graft 31.9{\%}; P<.01). Conclusion: Both embolization and stent grafts are safe therapeutic options for acute carotid blowout syndrome. Embolization for ICA/CCA carotid blowout syndrome was associated with higher risks of procedural stroke and lower recurrent bleeding compared to stent grafts.",
keywords = "Carotid blowout syndrome, Embolization, Endovascular, Stent graft, Systematic review",
author = "Wong, {Daniel J. Y.} and Christopher Donaldson and Lai, {Leon T.} and Andrew Coleman and Charles Giddings and Lee-Anne Slater and Chandra, {Ronil V.}",
year = "2018",
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journal = "Head & Neck",
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Safety and effectiveness of endovascular embolization or stent-graft reconstruction for treatment of acute carotid blowout syndrome in patients with head and neck cancer : Case series and systematic review of observational studies. / Wong, Daniel J. Y.; Donaldson, Christopher; Lai, Leon T.; Coleman, Andrew; Giddings, Charles; Slater, Lee-Anne; Chandra, Ronil V.

In: Head and Neck, Vol. 40, No. 4, 04.2018, p. 846-854.

Research output: Contribution to journalReview ArticleResearchpeer-review

TY - JOUR

T1 - Safety and effectiveness of endovascular embolization or stent-graft reconstruction for treatment of acute carotid blowout syndrome in patients with head and neck cancer

T2 - Case series and systematic review of observational studies

AU - Wong, Daniel J. Y.

AU - Donaldson, Christopher

AU - Lai, Leon T.

AU - Coleman, Andrew

AU - Giddings, Charles

AU - Slater, Lee-Anne

AU - Chandra, Ronil V.

PY - 2018/4

Y1 - 2018/4

N2 - Background: Indications for treatment and outcomes after endovascular management of carotid blowout syndrome for patients with head and neck cancer are not well defined. We investigated the safety and effectiveness of endovascular embolization and stent-graft reconstruction. Methods: A literature review was performed for studies published between 2001 and 2015 with relevance to treatment outcomes. Our institutional database was examined to identify patients treated with endovascular techniques. Results: A total of 266 patients were included. Rates of procedural stroke were higher after embolization of internal carotid artery (ICA)/common carotid artery (CCA) compared to stent graft (embolization 10.3%; stent graft 2.5%; P<.02). Stent graft of ICA/CCA was associated with higher rates of recurrent bleeding (embolization 9.1%; stent graft 31.9%; P<.01). Conclusion: Both embolization and stent grafts are safe therapeutic options for acute carotid blowout syndrome. Embolization for ICA/CCA carotid blowout syndrome was associated with higher risks of procedural stroke and lower recurrent bleeding compared to stent grafts.

AB - Background: Indications for treatment and outcomes after endovascular management of carotid blowout syndrome for patients with head and neck cancer are not well defined. We investigated the safety and effectiveness of endovascular embolization and stent-graft reconstruction. Methods: A literature review was performed for studies published between 2001 and 2015 with relevance to treatment outcomes. Our institutional database was examined to identify patients treated with endovascular techniques. Results: A total of 266 patients were included. Rates of procedural stroke were higher after embolization of internal carotid artery (ICA)/common carotid artery (CCA) compared to stent graft (embolization 10.3%; stent graft 2.5%; P<.02). Stent graft of ICA/CCA was associated with higher rates of recurrent bleeding (embolization 9.1%; stent graft 31.9%; P<.01). Conclusion: Both embolization and stent grafts are safe therapeutic options for acute carotid blowout syndrome. Embolization for ICA/CCA carotid blowout syndrome was associated with higher risks of procedural stroke and lower recurrent bleeding compared to stent grafts.

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