Saccadic eye movement characteristics in adult Niemann-Pick Type C Disease: Relationships with disease severity and brain structural measures

Larry Abel, Elizabeth Bowman, Dennis Velakoulis, Michael Collingwood Fahey, Patricia Desmond, Matthew D Macfarlane, Jeffrey Chee Leong Looi, Christopher Adamson, Mark Walterfang

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Niemann-Pick Type C disease (NPC) is a rare genetic disorder of lipid metabolism. A parameter related to horizontal saccadic peak velocity was one of the primary outcome measures in the clinical trial assessing miglustat as a treatment for NPC.
Original languageEnglish
Article number e50947
Number of pages7
JournalPLoS ONE
Volume7
Issue number11
DOIs
Publication statusPublished - 2012

Cite this

Abel, Larry ; Bowman, Elizabeth ; Velakoulis, Dennis ; Fahey, Michael Collingwood ; Desmond, Patricia ; Macfarlane, Matthew D ; Looi, Jeffrey Chee Leong ; Adamson, Christopher ; Walterfang, Mark. / Saccadic eye movement characteristics in adult Niemann-Pick Type C Disease: Relationships with disease severity and brain structural measures. In: PLoS ONE. 2012 ; Vol. 7, No. 11.
@article{85328272ad824abe8049607f135a8ce2,
title = "Saccadic eye movement characteristics in adult Niemann-Pick Type C Disease: Relationships with disease severity and brain structural measures",
abstract = "Niemann-Pick Type C disease (NPC) is a rare genetic disorder of lipid metabolism. A parameter related to horizontal saccadic peak velocity was one of the primary outcome measures in the clinical trial assessing miglustat as a treatment for NPC.",
author = "Larry Abel and Elizabeth Bowman and Dennis Velakoulis and Fahey, {Michael Collingwood} and Patricia Desmond and Macfarlane, {Matthew D} and Looi, {Jeffrey Chee Leong} and Christopher Adamson and Mark Walterfang",
year = "2012",
doi = "10.1371/journal.pone.0050947",
language = "English",
volume = "7",
journal = "PLoS ONE",
issn = "1932-6203",
publisher = "Public Library of Science",
number = "11",

}

Abel, L, Bowman, E, Velakoulis, D, Fahey, MC, Desmond, P, Macfarlane, MD, Looi, JCL, Adamson, C & Walterfang, M 2012, 'Saccadic eye movement characteristics in adult Niemann-Pick Type C Disease: Relationships with disease severity and brain structural measures' PLoS ONE, vol. 7, no. 11, e50947. https://doi.org/10.1371/journal.pone.0050947

Saccadic eye movement characteristics in adult Niemann-Pick Type C Disease: Relationships with disease severity and brain structural measures. / Abel, Larry; Bowman, Elizabeth; Velakoulis, Dennis; Fahey, Michael Collingwood; Desmond, Patricia; Macfarlane, Matthew D; Looi, Jeffrey Chee Leong; Adamson, Christopher; Walterfang, Mark.

In: PLoS ONE, Vol. 7, No. 11, e50947, 2012.

Research output: Contribution to journalArticleResearchpeer-review

TY - JOUR

T1 - Saccadic eye movement characteristics in adult Niemann-Pick Type C Disease: Relationships with disease severity and brain structural measures

AU - Abel, Larry

AU - Bowman, Elizabeth

AU - Velakoulis, Dennis

AU - Fahey, Michael Collingwood

AU - Desmond, Patricia

AU - Macfarlane, Matthew D

AU - Looi, Jeffrey Chee Leong

AU - Adamson, Christopher

AU - Walterfang, Mark

PY - 2012

Y1 - 2012

N2 - Niemann-Pick Type C disease (NPC) is a rare genetic disorder of lipid metabolism. A parameter related to horizontal saccadic peak velocity was one of the primary outcome measures in the clinical trial assessing miglustat as a treatment for NPC.

AB - Niemann-Pick Type C disease (NPC) is a rare genetic disorder of lipid metabolism. A parameter related to horizontal saccadic peak velocity was one of the primary outcome measures in the clinical trial assessing miglustat as a treatment for NPC.

U2 - 10.1371/journal.pone.0050947

DO - 10.1371/journal.pone.0050947

M3 - Article

VL - 7

JO - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

IS - 11

M1 - e50947

ER -