Saccadic eye movement characteristics in adult Niemann-Pick Type C Disease: Relationships with disease severity and brain structural measures

Larry Abel, Elizabeth Bowman, Dennis Velakoulis, Michael Collingwood Fahey, Patricia Desmond, Matthew D Macfarlane, Jeffrey Chee Leong Looi, Christopher Adamson, Mark Walterfang

Research output: Contribution to journalArticleResearchpeer-review

19 Citations (Scopus)

Abstract

Niemann-Pick Type C disease (NPC) is a rare genetic disorder of lipid metabolism. A parameter related to horizontal saccadic peak velocity was one of the primary outcome measures in the clinical trial assessing miglustat as a treatment for NPC.
Original languageEnglish
Article number e50947
Number of pages7
JournalPLoS ONE
Volume7
Issue number11
DOIs
Publication statusPublished - 2012

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