Saccadic eye movement characteristics in adult Niemann-Pick Type C Disease: Relationships with disease severity and brain structural measures

Larry Abel; Elizabeth Bowman; Dennis Velakoulis; Michael Collingwood Fahey; Patricia Desmond; Matthew D Macfarlane; Jeffrey Chee Leong Looi; Christopher Adamson; Mark Walterfang

doi:10.1371/journal.pone.0050947

Saccadic eye movement characteristics in adult Niemann-Pick Type C Disease: Relationships with disease severity and brain structural measures

Larry Abel, Elizabeth Bowman, Dennis Velakoulis, Michael Collingwood Fahey, Patricia Desmond, Matthew D Macfarlane, Jeffrey Chee Leong Looi, Christopher Adamson, Mark Walterfang

Paediatrics Monash Health

Research output: Contribution to journal › Article › Research › peer-review

19 Citations (Scopus)

Abstract

Niemann-Pick Type C disease (NPC) is a rare genetic disorder of lipid metabolism. A parameter related to horizontal saccadic peak velocity was one of the primary outcome measures in the clinical trial assessing miglustat as a treatment for NPC.

Original language	English
Article number	e50947
Number of pages	7
Journal	PLoS ONE
Volume	7
Issue number	11
DOIs	https://doi.org/10.1371/journal.pone.0050947
Publication status	Published - 2012

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10.1371/journal.pone.0050947Licence: CC BY

Cite this

Abel, Larry ; Bowman, Elizabeth ; Velakoulis, Dennis ; Fahey, Michael Collingwood ; Desmond, Patricia ; Macfarlane, Matthew D ; Looi, Jeffrey Chee Leong ; Adamson, Christopher ; Walterfang, Mark. / Saccadic eye movement characteristics in adult Niemann-Pick Type C Disease: Relationships with disease severity and brain structural measures. In: PLoS ONE. 2012 ; Vol. 7, No. 11.

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abstract = "Niemann-Pick Type C disease (NPC) is a rare genetic disorder of lipid metabolism. A parameter related to horizontal saccadic peak velocity was one of the primary outcome measures in the clinical trial assessing miglustat as a treatment for NPC.",

author = "Larry Abel and Elizabeth Bowman and Dennis Velakoulis and Fahey, {Michael Collingwood} and Patricia Desmond and Macfarlane, {Matthew D} and Looi, {Jeffrey Chee Leong} and Christopher Adamson and Mark Walterfang",

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Saccadic eye movement characteristics in adult Niemann-Pick Type C Disease: Relationships with disease severity and brain structural measures. / Abel, Larry; Bowman, Elizabeth; Velakoulis, Dennis; Fahey, Michael Collingwood; Desmond, Patricia; Macfarlane, Matthew D; Looi, Jeffrey Chee Leong; Adamson, Christopher; Walterfang, Mark.

In: PLoS ONE, Vol. 7, No. 11, e50947, 2012.

Research output: Contribution to journal › Article › Research › peer-review

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AU - Desmond, Patricia

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AU - Looi, Jeffrey Chee Leong

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AU - Walterfang, Mark

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