Skip to main navigation Skip to search Skip to main content

S -> N type Smiles rearrangement of the aminoethanethiol moiety attached to heterocyclic compounds

Research output: Contribution to journalArticleResearchpeer-review

Abstract

Base catalysed S -> N type Smiles rearrangement of aminoethanethiol-substituted pyridine and triazine compounds led to formation of the corresponding thiol or disulfide compounds. Prior to rearrangement, the heteroaryl sulfanylethylamines could be prepared in high yields as the hydrochloride or trifluoroacetate salts from the corresponding tert-BOC protected amine. (C) 2010 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)3452 - 3456
Number of pages5
JournalTetrahedron
Volume66
Issue number19
DOIs
Publication statusPublished - 2010

Cite this