Role of the second extracellular loop of the adenosine A₁ receptor on allosteric modulator binding, signaling, and cooperativity

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• Finished

  Understanding mechanisms of allostery and biased agonism at the adenosine A1 receptor

  Christopoulos, A., May, L., Scammells, P. & Scott, D.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/15 → 31/12/17

  Project: Research

• Adenosine Receptor Biased Agonism to Treat Ischaemic Heart Disease

  May, L., Scammells, P., Wang, B. & White, P.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/15 → 31/12/17

  Project: Research

• The Janus face of G Protein-Coupled Receptors: Implications for Disease Mechanisms and Opportunities for Drug Discovery

  Sexton, P., Bunnett, N., Christopoulos, A. & Summers, R.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/14 → 31/12/18

  Project: Research

• Allosteric Fingerprinting of G Protein-Coupled Receptor Monomers and Oligomers

  May, L.

  Australian Research Council (ARC)

  1/01/13 → 16/11/16

  Project: Research

• Positive allosteric modulation of metabotropic glutamate receptor 5; a novel approach for the treatment of schizophrenia and cognitive disorders

  Gregory, K.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/11 → 31/12/15

  Project: Research

• Allosteric modulation of GPCR-mediated intracellular signalling in human embryonic stem cell derived cardiomyocytes.

  May, L.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/08 → 30/09/12

  Project: Research

• NHMRC Principal Research Fellow

  Sexton, P.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/06 → 31/12/18

  Project: Research

• NHMRC Research Fellowship

  Christopoulos, A.

  National Health and Medical Research Council (NHMRC) (Australia)

  1/01/05 → 31/12/20

  Project: Research