Role of the kidney in the fetal programming of adult cardiovascular disease: an update

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Abstract

It is well established that an adverse in utero environment can impinge upon fetal development and place the offspring on a track leading to future cardiovascular disease. Significantly, this may occur in the absence of any outward manifestations at birth. In this brief review, we focus on potential renal mechanisms that lead to adaptations in glomerular and tubular function that initiate hypertension of developmental origin and examine potential therapeutic interventions. This report updates recent data in this field.
Original languageEnglish
Pages (from-to)53 - 59
Number of pages7
JournalCurrent Opinion in Pharmacology
Volume21
DOIs
Publication statusPublished - 2015

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