RNA-binding proteins that target the androgen receptor mRNA

Jackie A. Wilce; Peter J. Leedman; M. C J Wilce

doi:10.1080/15216540216033

RNA-binding proteins that target the androgen receptor mRNA

Jackie A. Wilce, Peter J. Leedman, M. C J Wilce

Research output: Contribution to journal › Review Article › Research › peer-review

10 Citations (Scopus)

Abstract

Recent efforts to elucidate mechanisms of posttranscriptional gene regulation have resulted in the description of both cis- and trans-acting factors which affect the stability and translational efficiency of specific mRNAs. Here we summarise some of the concepts in this field, with particular attention to recently discovered protein/RNA interactions involving the human androgen receptor mRNA. Such systems are of interest for their potential as targets for the modulation of protein production.

Original language	English
Pages (from-to)	345-349
Number of pages	5
Journal	IUBMB Life
Volume	54
Issue number	6
DOIs	https://doi.org/10.1080/15216540216033
Publication status	Published - 1 Dec 2002
Externally published	Yes

Keywords

Androgen receptor, HuR
MRNA stability
Poly(C)-binding proteins
Posttranscriptional regulation
RNA-binding protein

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10.1080/15216540216033

Cite this

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AB - Recent efforts to elucidate mechanisms of posttranscriptional gene regulation have resulted in the description of both cis- and trans-acting factors which affect the stability and translational efficiency of specific mRNAs. Here we summarise some of the concepts in this field, with particular attention to recently discovered protein/RNA interactions involving the human androgen receptor mRNA. Such systems are of interest for their potential as targets for the modulation of protein production.

KW - Androgen receptor, HuR

KW - MRNA stability

KW - Poly(C)-binding proteins

KW - Posttranscriptional regulation

KW - RNA-binding protein

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RNA-binding proteins that target the androgen receptor mRNA

Abstract

Keywords

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