TY - JOUR
T1 - Risk of maternal and neonatal complications in subsequent pregnancy after planned caesarean section in a first birth, compared with emergency caesarean section
T2 - A nationwide comparative cohort study
AU - Kok, N.
AU - Ruiter, L.
AU - Hof, M.
AU - Ravelli, A.
AU - Mol, B. W.
AU - Pajkrt, E.
AU - Kazemier, B.
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Objective To compare the difference in risks of neonatal and maternal complications, including uterine rupture, in a second birth following a planned caesarean section versus emergency caesarean section in the first birth. Design Prospective cohort study. Setting Population-based cohort in the Netherlands. Population Linked data set of outcomes for term caesarean section in a first birth followed by a consecutive delivery. Methods We conducted a prospective cohort analysis using data from the Dutch Perinatal Registry. We included primiparous women who gave birth to term singleton infants through planned or emergency caesarean from January 2000 through December 2007, and who had a second singleton delivery during the same period (n = 41 109). Odds ratios and adjusted odds ratios were calculated. Main outcome measures Maternal and neonatal complications, specifically uterine rupture, in second births associated with planned and emergency caesareans in the first birth. Results Women with a history of a planned caesarean section in the first birth (n = 11 445) had a 0.24% risk for uterine rupture, compared with a 0.16% risk for women with a history of emergency caesarean section (n = 29 664; aOR 1.4, 95% CI 0.8-2.4). In multivariate logistic regression, women with planned caesareans in a first birth had a significantly increased risk of stillbirth (aOR 1.5, 95% CI 1.0-2.2) and postpartum haemorrhage (aOR 1.1, 95% CI 1.0-1.2) in second births, compared with women with emergency caesareans in the first birth. Conclusions We found a moderately increased risk of postpartum haemorrhage and a small to moderately increased risk of uterine rupture and stillbirth as a long-term effect of prior planned caesarean delivery on second births.
AB - Objective To compare the difference in risks of neonatal and maternal complications, including uterine rupture, in a second birth following a planned caesarean section versus emergency caesarean section in the first birth. Design Prospective cohort study. Setting Population-based cohort in the Netherlands. Population Linked data set of outcomes for term caesarean section in a first birth followed by a consecutive delivery. Methods We conducted a prospective cohort analysis using data from the Dutch Perinatal Registry. We included primiparous women who gave birth to term singleton infants through planned or emergency caesarean from January 2000 through December 2007, and who had a second singleton delivery during the same period (n = 41 109). Odds ratios and adjusted odds ratios were calculated. Main outcome measures Maternal and neonatal complications, specifically uterine rupture, in second births associated with planned and emergency caesareans in the first birth. Results Women with a history of a planned caesarean section in the first birth (n = 11 445) had a 0.24% risk for uterine rupture, compared with a 0.16% risk for women with a history of emergency caesarean section (n = 29 664; aOR 1.4, 95% CI 0.8-2.4). In multivariate logistic regression, women with planned caesareans in a first birth had a significantly increased risk of stillbirth (aOR 1.5, 95% CI 1.0-2.2) and postpartum haemorrhage (aOR 1.1, 95% CI 1.0-1.2) in second births, compared with women with emergency caesareans in the first birth. Conclusions We found a moderately increased risk of postpartum haemorrhage and a small to moderately increased risk of uterine rupture and stillbirth as a long-term effect of prior planned caesarean delivery on second births.
KW - Emergency caesarean section
KW - planned caesarean section
KW - postpartum haemorrhage
KW - stillbirth
KW - uterine rupture
KW - vaginal birth after caesarean
UR - http://www.scopus.com/inward/record.url?scp=84891357910&partnerID=8YFLogxK
U2 - 10.1111/1471-0528.12483
DO - 10.1111/1471-0528.12483
M3 - Article
AN - SCOPUS:84891357910
SN - 1470-0328
VL - 121
SP - 216
EP - 223
JO - BJOG: An International Journal of Obstetrics and Gynaecology
JF - BJOG: An International Journal of Obstetrics and Gynaecology
IS - 2
ER -