Purpose: To describe the incidence and risk factors for ocular hypertension and/or glaucoma in patients with Fuchs heterochromic iridocyclitis (FHC). Methods: Retrospective analysis of 88 patients with FHC. Kaplan–Meier curves estimated the time to develop cataract and ocular hypertension/glaucoma. Possible prognostic factors were investigated in univariate Kaplan–Meier analyses using the Mantel–Cox logrank test. Results: At presentation with FHC, 52% of patients had a cataract and 26% of patients had ocular hypertension/glaucoma. The estimated percentage of patients with a cataract or ocular hypertension/glaucoma by 4 years after presentation was 71% (CI: 58–81%) and 39% (CI: 28–51%), respectively. Patients aged ≥50 years had significantly greater risk of developing glaucoma (p = 0.0065). After adjusting for age-group, having a cataract at presentation was associated with increased risk of glaucoma (p = 0.032). Conclusions: Risk factors for development of ocular hypertension/glaucoma were increasing patient age and having a cataract at presentation with FHC.