Projects per year
Abstract
An efficient and expedient route to the synthesis of dicarba peptides from protecting group-free sequences is reported using Ru-alkylidene catalysed olefin metathesis. A range of cyclic peptides was prepared from linear peptides containing two Z-crotyl glycine residues. Free amine groups were masked as salts with Brønsted acids preventing in situ catalyst decomposition. Excellent RCM conversion was obtained in both DMF and methanol.
Original language | English |
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Pages (from-to) | 9769-9772 |
Number of pages | 4 |
Journal | Chemical Communications |
Volume | 53 |
Issue number | 70 |
DOIs | |
Publication status | Published - 2017 |
Projects
- 1 Finished
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New metal catalysed tandem routes to nitrogen containing compounds
Robinson, A. & Jackson, R.
Australian Research Council (ARC)
3/01/12 → 6/01/15
Project: Research