Ring-closing metathesis in peptides

Ellen C. Gleeson, W. Roy Jackson, Andrea J. Robinson

Research output: Contribution to journalReview ArticleResearchpeer-review

29 Citations (Scopus)

Abstract

This review highlights developments in the field of ring-closing metathesis applied to the synthesis of cyclic peptides. Special attention is focussed on the synthesis of dicarba peptides that mimic native cystine containing peptides. Recent advances in the field are discussed, including the stereoselective synthesis of carbon-bridged peptides and RCM in aqueous media.

Original languageEnglish
Pages (from-to)4325-4333
Number of pages9
JournalTetrahedron Letters
Volume57
Issue number39
DOIs
Publication statusPublished - 28 Sep 2016

Keywords

  • Cyclic constraints
  • Dicarba peptides
  • Olefin metathesis
  • Peptides
  • Ring-closing metathesis

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