Rifaximin (4-deoxy-4'-methylpyrido[1',2'-1,2]imidazole- [5,4c]-rifamycin SV) is a synthetic antimicrobial and derivative of rifamycin (Jiang and DuPont, 2005; Scarpignato and Pelosini, 2005; Finegold et al., 2009). It was first described as compound L-105 in 1982 and marketed in Italy in 1987 (Huang and DuPont, 2005; Scarpignato and Pelosini, 2005). Its empirical formula is C43H51N3O11 and its molecular weight is 785.9 Da; the chemical structure is shown in Figure 128.1.
|Title of host publication||Kucers the Use of Antibiotics|
|Subtitle of host publication||A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs|
|Editors||M. Lindsay Grayson|
|Place of Publication||Boca Raton FL USA|
|Number of pages||13|
|Publication status||Published - 2 Oct 2017|