Abstract
Rifaximin (4-deoxy-4'-methylpyrido[1',2'-1,2]imidazole- [5,4c]-rifamycin SV) is a synthetic antimicrobial and derivative of rifamycin (Jiang and DuPont, 2005; Scarpignato and Pelosini, 2005; Finegold et al., 2009). It was first described as compound L-105 in 1982 and marketed in Italy in 1987 (Huang and DuPont, 2005; Scarpignato and Pelosini, 2005). Its empirical formula is C43H51N3O11 and its molecular weight is 785.9 Da; the chemical structure is shown in Figure 128.1.
Original language | English |
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Title of host publication | Kucers the Use of Antibiotics |
Subtitle of host publication | A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs |
Editors | M. Lindsay Grayson |
Place of Publication | Boca Raton FL USA |
Publisher | CRC Press |
Chapter | 128 |
Pages | 2450-2462 |
Number of pages | 13 |
Edition | 7th |
ISBN (Electronic) | 9781498747967 |
ISBN (Print) | 9781498747950 |
Publication status | Published - 2 Oct 2017 |