Abstract
Rifaximin (4-deoxy-4'-methylpyrido[1',2'-1,2]imidazole- [5,4c]-rifamycin SV) is a synthetic antimicrobial and derivative of rifamycin (Jiang and DuPont, 2005; Scarpignato and Pelosini, 2005; Finegold et al., 2009). It was first described as compound L-105 in 1982 and marketed in Italy in 1987 (Huang and DuPont, 2005; Scarpignato and Pelosini, 2005). Its empirical formula is C43H51N3O11 and its molecular weight is 785.9 Da; the chemical structure is shown in Figure 128.1.
| Original language | English |
|---|---|
| Title of host publication | Kucers the Use of Antibiotics |
| Subtitle of host publication | A Clinical Review of Antibacterial, Antifungal, Antiparasitic, and Antiviral Drugs |
| Editors | M. Lindsay Grayson |
| Place of Publication | Boca Raton FL USA |
| Publisher | CRC Press |
| Chapter | 128 |
| Pages | 2450-2462 |
| Number of pages | 13 |
| Edition | 7th |
| ISBN (Electronic) | 9781498747967 |
| ISBN (Print) | 9781498747950 |
| Publication status | Published - 2 Oct 2017 |