Rifampicin-associated segmental necrotizing glomerulonephritis in staphylococcal endocarditis

Kathryn J Wiggins, Jason W. Galanos, Prue A. Hill, Kirsten V. Scott, Robyn G. Langham

Research output: Contribution to journalReview ArticleResearchpeer-review

4 Citations (Scopus)


Segmental necrotising glomerulonephritis has been reported as complication of rifampicin therapy in patients receiving treatment for tuberculosis. Changing epidemiology of infections such as infective endocarditis (IE) has led to an increase in the use of rifampicin for Staphylococcal infections. We describe a case of a patient with Staphylococcal IE who developed acute renal failure secondary to a segmental necrotising glomerulonephritis while being treated with rifampicin, and review the literature regarding this complication of rifampicin therapy.

Original languageEnglish
Pages (from-to)489-494
Number of pages6
JournalJournal of Nephrology
Issue number4
Publication statusPublished - Jul 2007
Externally publishedYes


  • Acute renal failure
  • Antibiotic-related toxicity
  • Bacterial endocarditis
  • Rifampicin
  • Segmental necrotizing glomerulonephritis
  • Staphylococcus aureus

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