Abstract
Ribozymes are a class of ribonucleic acid (RNA) molecules that possess enzymatic properties. Upon binding to complementary nucleic acid strands, catalytic degradation occurs via a cleavage reaction. In effect, inactivation of susceptible substrate RNA molecules take place at a catalytic rate and with a high degree of substrate specificity. This review deals with the structure, design and potential applications of ribozymes in medicine.
| Original language | English |
|---|---|
| Pages (from-to) | 507-512 |
| Number of pages | 6 |
| Journal | Medical Science Research |
| Volume | 27 |
| Issue number | 8 |
| Publication status | Published - 1999 |
| Externally published | Yes |
Keywords
- Catalytic RNA
- Ribozyme
- Ribozyme therapy
- RNA structure