Ribozymes: Structure and potential applications in medicine

Asad U. Khan, Sunil K. Lal

Research output: Contribution to journalReview ArticleResearchpeer-review

5 Citations (Scopus)


Ribozymes are a class of ribonucleic acid (RNA) molecules that possess enzymatic properties. Upon binding to complementary nucleic acid strands, catalytic degradation occurs via a cleavage reaction. In effect, inactivation of susceptible substrate RNA molecules take place at a catalytic rate and with a high degree of substrate specificity. This review deals with the structure, design and potential applications of ribozymes in medicine.

Original languageEnglish
Pages (from-to)507-512
Number of pages6
JournalMedical Science Research
Issue number8
Publication statusPublished - 1999
Externally publishedYes


  • Catalytic RNA
  • Ribozyme
  • Ribozyme therapy
  • RNA structure

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