Abstract
Rhodium catalysis has been extensively used for ortho-C-H functionalization reactions, and successfully extended to meta-C-H functionalization. Its application to para-C-H activation remains an unmet challenge. Herein we disclose the first example of such a reaction, with the Rh-catalyzed para-C-H olefination of arenes. The use of a Si-linked cyanobiphenyl unit as a traceless directing group leads to highly para-selective arene-olefin couplings.
Original language | English |
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Pages (from-to) | 7426-7432 |
Number of pages | 7 |
Journal | Chemical Science |
Volume | 10 |
Issue number | 31 |
DOIs | |
Publication status | Published - 21 Aug 2019 |