REVIEW: Delivery of nascent polypeptides to the mitochondrial surface

Travis Clarke Beddoe; Trevor James Lithgow

REVIEW: Delivery of nascent polypeptides to the mitochondrial surface

Travis Clarke Beddoe, Trevor James Lithgow

Biochemistry & Molecular Biology

Research output: Contribution to journal › Article › Research › peer-review

Abstract

Thousands of polypeptides with diverse biochemical properties, some of which are extremely hydrophobic, are targeted from cytoplasmic ribosomes to the surface of mitochondria. Localised synthesis, as well as transient interactions with a wide array of molecular chaperones and other cytoplasmic factors, can promote productive interaction of mitochondrial proteins with the TOM complex to initiate protein import into mitochondria.

Original language	English
Pages (from-to)	35 - 39
Number of pages	5
Journal	BBA Molecular Cell Research
Volume	1592
Issue number	1
Publication status	Published - 2002

Cite this

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title = "REVIEW: Delivery of nascent polypeptides to the mitochondrial surface",

abstract = "Thousands of polypeptides with diverse biochemical properties, some of which are extremely hydrophobic, are targeted from cytoplasmic ribosomes to the surface of mitochondria. Localised synthesis, as well as transient interactions with a wide array of molecular chaperones and other cytoplasmic factors, can promote productive interaction of mitochondrial proteins with the TOM complex to initiate protein import into mitochondria.",

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AB - Thousands of polypeptides with diverse biochemical properties, some of which are extremely hydrophobic, are targeted from cytoplasmic ribosomes to the surface of mitochondria. Localised synthesis, as well as transient interactions with a wide array of molecular chaperones and other cytoplasmic factors, can promote productive interaction of mitochondrial proteins with the TOM complex to initiate protein import into mitochondria.

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M3 - Article

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SP - 35

EP - 39

JO - BBA Molecular Cell Research

JF - BBA Molecular Cell Research

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REVIEW: Delivery of nascent polypeptides to the mitochondrial surface

Abstract

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