Review: Beta-thalassemia and molecular chaperones

Afshan Sumera; Ammu Radhakrishnan; Abdul Aziz Baba; Elizabeth George

doi:10.1016/j.bcmd.2015.01.008

Review: Beta-thalassemia and molecular chaperones

Afshan Sumera, Ammu Radhakrishnan, Abdul Aziz Baba, Elizabeth George

Research output: Contribution to journal › Review Article › Research › peer-review

10 Citations (Scopus)

Abstract

Thalassemia is known as a diverse single gene disorder, which is prevalent worldwide. The molecular chaperones are set of proteins that help in two important processes while protein synthesis and degradation include folding or unfolding and assembly or disassembly, thereby helping in cell homeostasis. This review recaps current knowledge regarding the role of molecular chaperones in thalassemia, with a focus on beta thalassemia.

Original language	English
Pages (from-to)	348-352
Number of pages	5
Journal	Blood Cells, Molecules, and Diseases
Volume	54
Issue number	4
DOIs	https://doi.org/10.1016/j.bcmd.2015.01.008
Publication status	Published - Apr 2015
Externally published	Yes

Keywords

AHSP
HSP-70
Molecular chaperones
Thalassemia

Access to Document

10.1016/j.bcmd.2015.01.008

Cite this

@article{546e764457d14f419379346787cc1af9,

title = "Review: Beta-thalassemia and molecular chaperones",

abstract = "Thalassemia is known as a diverse single gene disorder, which is prevalent worldwide. The molecular chaperones are set of proteins that help in two important processes while protein synthesis and degradation include folding or unfolding and assembly or disassembly, thereby helping in cell homeostasis. This review recaps current knowledge regarding the role of molecular chaperones in thalassemia, with a focus on beta thalassemia.",

keywords = "AHSP, HSP-70, Molecular chaperones, Thalassemia",

author = "Afshan Sumera and Ammu Radhakrishnan and Baba, {Abdul Aziz} and Elizabeth George",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",

year = "2015",

month = apr,

doi = "10.1016/j.bcmd.2015.01.008",

language = "English",

volume = "54",

pages = "348--352",

journal = "Blood Cells, Molecules, and Diseases",

issn = "1079-9796",

publisher = "Elsevier",

number = "4",

}

TY - JOUR

T1 - Review

T2 - Beta-thalassemia and molecular chaperones

AU - Sumera, Afshan

AU - Radhakrishnan, Ammu

AU - Baba, Abdul Aziz

AU - George, Elizabeth

PY - 2015/4

Y1 - 2015/4

N2 - Thalassemia is known as a diverse single gene disorder, which is prevalent worldwide. The molecular chaperones are set of proteins that help in two important processes while protein synthesis and degradation include folding or unfolding and assembly or disassembly, thereby helping in cell homeostasis. This review recaps current knowledge regarding the role of molecular chaperones in thalassemia, with a focus on beta thalassemia.

AB - Thalassemia is known as a diverse single gene disorder, which is prevalent worldwide. The molecular chaperones are set of proteins that help in two important processes while protein synthesis and degradation include folding or unfolding and assembly or disassembly, thereby helping in cell homeostasis. This review recaps current knowledge regarding the role of molecular chaperones in thalassemia, with a focus on beta thalassemia.

KW - AHSP

KW - HSP-70

KW - Molecular chaperones

KW - Thalassemia

UR - http://www.scopus.com/inward/record.url?scp=84926139343&partnerID=8YFLogxK

U2 - 10.1016/j.bcmd.2015.01.008

DO - 10.1016/j.bcmd.2015.01.008

M3 - Review Article

C2 - 25648458

AN - SCOPUS:84926139343

SN - 1079-9796

VL - 54

SP - 348

EP - 352

JO - Blood Cells, Molecules, and Diseases

JF - Blood Cells, Molecules, and Diseases

IS - 4

ER -

Review: Beta-thalassemia and molecular chaperones

Abstract

Keywords

Access to Document

Other files and links

Cite this