Abstract
| Original language | English |
|---|---|
| Pages (from-to) | 451 - 460 |
| Number of pages | 10 |
| Journal | American Journal of Tropical Medicine and Hygiene |
| Volume | 91 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2014 |
Cite this
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Review article: Rickettsial infections in Southeast Asia: implications for local populace and febrile returned travelers. / Aung, Ar Kar; Spelman, Dennis; Murray, Ronan John; Graves, Stephen R.
In: American Journal of Tropical Medicine and Hygiene, Vol. 91, No. 3, 2014, p. 451 - 460.Research output: Contribution to journal › Article › Research › peer-review
TY - JOUR
T1 - Review article: Rickettsial infections in Southeast Asia: implications for local populace and febrile returned travelers
AU - Aung, Ar Kar
AU - Spelman, Dennis
AU - Murray, Ronan John
AU - Graves, Stephen R
PY - 2014
Y1 - 2014
N2 - Rickettsial infections represent a major cause of non-malarial febrile illnesses among the residents of Southeast Asia and returned travelers from that region. There are several challenges in recognition, diagnosis, and management of rickettsioses endemic to Southeast Asia. This review focuses on the prevalent rickettsial infections, namely, murine typhus (Rickettsia typhi), scrub typhus (Orientia tsutsugamushi), and members of spotted fever group rickettsiae. Information on epidemiology and regional variance in the prevalence of rickettsial infections is analyzed. Clinical characteristics of main groups of rickettsioses, unusual presentations, and common pitfalls in diagnosis are further discussed. In particular, relevant epidemiologic and clinical aspects on emerging spotted fever group rickettsiae in the region, such as Rickettsia honei, R. felis, R. japonica, and R. helvetica, are presented. Furthermore, challenges in laboratory diagnosis and management aspects of rickettsial infections unique to Southeast Asia are discussed, and data on emerging resistance to antimicrobial drugs and treatment/prevention options are also reviewed.
AB - Rickettsial infections represent a major cause of non-malarial febrile illnesses among the residents of Southeast Asia and returned travelers from that region. There are several challenges in recognition, diagnosis, and management of rickettsioses endemic to Southeast Asia. This review focuses on the prevalent rickettsial infections, namely, murine typhus (Rickettsia typhi), scrub typhus (Orientia tsutsugamushi), and members of spotted fever group rickettsiae. Information on epidemiology and regional variance in the prevalence of rickettsial infections is analyzed. Clinical characteristics of main groups of rickettsioses, unusual presentations, and common pitfalls in diagnosis are further discussed. In particular, relevant epidemiologic and clinical aspects on emerging spotted fever group rickettsiae in the region, such as Rickettsia honei, R. felis, R. japonica, and R. helvetica, are presented. Furthermore, challenges in laboratory diagnosis and management aspects of rickettsial infections unique to Southeast Asia are discussed, and data on emerging resistance to antimicrobial drugs and treatment/prevention options are also reviewed.
UR - http://www.ncbi.nlm.nih.gov/pubmed/24957537
U2 - 10.4269/ajtmh.14-0191
DO - 10.4269/ajtmh.14-0191
M3 - Article
VL - 91
SP - 451
EP - 460
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
SN - 0002-9637
IS - 3
ER -